Searchable abstracts of presentations at key conferences in endocrinology

ea0019p205 | Growth and development | SFEBES2009

Exposure to a maternal dietary protein restriction during gestation impedes hepatoblast differentiation

Simpson E , Welham S

Maternal undernutrition has been demonstrated to impact upon the development of a number of organ systems, including the kidney and pancreas. Offspring exposed to a maternal dietary protein restriction during gestation exhibit livers with fewer, larger lobules, suggestive of a similar developmental defect. It has been previously suggested that developmental changes, at least in the kidney, might be mediated by a change in the expression of the transcription factor Prox1. Here,...